PCSK1 — Proprotein convertase subtilisin/kexin type 1
PCSK1 belongs to a gene co-expression module in 1 of 28 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.
PCSK1's module in each cell type
| Cell type | Module | Shares the module with | |
|---|---|---|---|
| Goblet cells | Secreted Antimicrobials Immune function | FAM3D, IFI6, IGFBP2, KLK11, KLK12, NBL1, NOXO1, REG1A +6 more | View in SCUBA |
About the gene
| Synonyms | NEC1, PC1, PC1/3, PC3, SPC3 |
|---|---|
| Chromosome | 5: 96390333-96434143 |
| Predicted location | Intracellular, Secreted |
| Essential gene | No |
| Protein class | Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted secreted proteins |
| Molecular function | Hydrolase, Protease, Serine protease |
Function
Involved in the processing of hormone and other protein precursors at sites comprised of pairs of basic amino acid residues. Substrates include POMC, renin, enkephalin, dynorphin, somatostatin, insulin and AGRP
Human Protein Atlas · Open Targets · UniProt
Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.