PCYT1A — Phosphate cytidylyltransferase 1A, choline
PCYT1A belongs to a gene co-expression module in 1 of 28 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.
PCYT1A's module in each cell type
| Cell type | Module | Shares the module with | |
|---|---|---|---|
| Gamma-delta T cells | TGF-beta Signaling Immune regulation | ABCF1, ABHD12, ACAP2, ADIPOR2, CBX6, ENPP4, FBXO9, GSAP +18 more |
About the gene
| Synonyms | CCTalpha, CT, CTPCT, PCYT1 |
|---|---|
| Chromosome | 3: 196214222-196287957 |
| Predicted location | Intracellular |
| Essential gene | Yes |
| Protein class | Disease related genes, Enzymes, Essential proteins, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins |
| Molecular function | Nucleotidyltransferase, Transferase |
| Biological process | Lipid biosynthesis, Lipid metabolism, Phospholipid biosynthesis, Phospholipid metabolism |
Function
Catalyzes the key rate-limiting step in the CDP-choline pathway for phosphatidylcholine biosynthesis.
Human Protein Atlas · Open Targets · UniProt
Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.