PGAM2 — Phosphoglycerate mutase 2
PGAM2 belongs to a gene co-expression module in 1 of 28 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.
PGAM2's module in each cell type
| Cell type | Module | Shares the module with | |
|---|---|---|---|
| Smooth muscle cells | Myogenic Cytoskeletal Program Contractility | CARHSP1, GADD45G, ITGB1BP1, MGST2, MYOZ1, NDUFV2, PDCL3, RALY +3 more | View in SCUBA |
About the gene
| Synonyms | PGAM-M |
|---|---|
| Chromosome | 7: 44062727-44065567 |
| Predicted location | Intracellular |
| Essential gene | No |
| Protein class | Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins |
| Molecular function | Hydrolase, Isomerase |
| Biological process | Glycolysis |
Function
Interconversion of 3- and 2-phosphoglycerate with 2,3- bisphosphoglycerate as the primer of the reaction. Can also catalyze the reaction of EC 5.4.2.4 (synthase), but with a reduced activity
Human Protein Atlas · Open Targets · UniProt
Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.