RALY — RALY heterogeneous nuclear ribonucleoprotein
RALY belongs to a gene co-expression module in 4 of 28 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.
RALY's module in each cell type
| Cell type | Module | Shares the module with | |
|---|---|---|---|
| CD8⁺ T cells | Mitochondrial ETC/OxPhos Mitochondrial & OxPhos | AP2S1, BAX, COX6A1, ERH, HSD17B10, LSM2, MAD2L2, MEA1 +7 more | View in SCUBA |
| Gamma-delta T cells | Transcriptional Elongation Control DNA/chromatin regulation | ANP32B, AP2M1, ARF5, AURKAIP1, CCDC124, CUEDC2, CYC1, DCTN3 +19 more | |
| Innate lymphoid cells | ILC1 Cytoskeletal Metabolic Cytoskeleton & motility | ATP5F1B, ATXN10, CCT7, CD82, DNPH1, GADD45GIP1, HMGA1, MEA1 +14 more | View in SCUBA |
| Smooth muscle cells | Myogenic Cytoskeletal Program Contractility | CARHSP1, GADD45G, ITGB1BP1, MGST2, MYOZ1, NDUFV2, PDCL3, PGAM2 +3 more | View in SCUBA |
About the gene
| Synonyms | HNRPCL2, P542 |
|---|---|
| Chromosome | 20: 33993646-34108308 |
| Predicted location | Intracellular |
| Essential gene | No |
| Protein class | Plasma proteins, Predicted intracellular proteins |
| Molecular function | Ribonucleoprotein, RNA-binding |
| Biological process | mRNA processing, mRNA splicing, Transcription, Transcription regulation |
Function
RNA-binding protein that acts as a transcriptional cofactor for cholesterol biosynthetic genes in the liver. Binds the lipid- responsive non-coding RNA LeXis and is required for LeXis-mediated effect on cholesterogenesis (By similarity). May be a heterogeneous nuclear ribonucleoprotein (hnRNP)
Human Protein Atlas · Open Targets · UniProt
Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.