POLM — DNA polymerase mu
POLM belongs to a gene co-expression module in 1 of 28 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.
POLM's module in each cell type
| Cell type | Module | Shares the module with | |
|---|---|---|---|
| Gamma-delta T cells | Ubiquitin Protein Quality Protein processing & ER | CHMP7, CLCN3, EDEM3, GART, GOPC, HERC4, KRIT1, LRIF1 +13 more |
About the gene
| Synonyms | Tdt-N |
|---|---|
| Chromosome | 7: 44072062-44082530 |
| Predicted location | Intracellular |
| Essential gene | No |
| Protein class | Enzymes, Metabolic proteins, Predicted intracellular proteins |
| Molecular function | DNA-directed DNA polymerase, Nucleotidyltransferase, Transferase |
| Biological process | DNA damage, DNA recombination, DNA repair |
Function
Gap-filling polymerase involved in repair of DNA double- strand breaks by non-homologous end joining (NHEJ). Participates in immunoglobulin (Ig) light chain gene rearrangement in V(D)J recombination.
Human Protein Atlas · Open Targets · UniProt
Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.