PPP3CC — Protein phosphatase 3 catalytic subunit gamma
PPP3CC belongs to a gene co-expression module in 1 of 28 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.
PPP3CC's module in each cell type
| Cell type | Module | Shares the module with | |
|---|---|---|---|
| Gamma-delta T cells | TGF-beta Signaling Immune regulation | ABCF1, ABHD12, ACAP2, ADIPOR2, CBX6, ENPP4, FBXO9, GSAP +18 more |
About the gene
| Synonyms | CALNA3, PP2Bgamma |
|---|---|
| Chromosome | 8: 22440819-22541142 |
| Predicted location | Intracellular |
| Essential gene | No |
| Protein class | Enzymes, Plasma proteins, Predicted intracellular proteins |
| Molecular function | Calmodulin-binding, Hydrolase, Protein phosphatase |
Function
Calcium-dependent, calmodulin-stimulated protein phosphatase which plays an essential role in the transduction of intracellular Ca(2+)-mediated signals. Dephosphorylates and activates transcription factor NFATC1. Dephosphorylates and inactivates transcription factor ELK1. Dephosphorylates DARPP32
Human Protein Atlas · Open Targets · UniProt
Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.