PROK2 — Prokineticin 2
PROK2 belongs to a gene co-expression module in 1 of 28 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.
PROK2's module in each cell type
| Cell type | Module | Shares the module with | |
|---|---|---|---|
| Neutrophils | Interferon Stimulated Genes Antiviral | ADAM8, APOBEC3A, BCL3, DDX60L, GBP2, MEFV, MIDN, MKNK2 +1 more |
About the gene
| Synonyms | BV8, KAL4, MIT1, PK2 |
|---|---|
| Chromosome | 3: 71771655-71785206 |
| Predicted location | Secreted |
| Essential gene | No |
| Protein class | Disease related genes, Human disease related genes, Predicted secreted proteins |
| Molecular function | Neuropeptide |
| Biological process | Biological rhythms |
Function
May function as an output molecule from the suprachiasmatic nucleus (SCN) that transmits behavioral circadian rhythm. May also function locally within the SCN to synchronize output. Potently contracts gastrointestinal (GI) smooth muscle
Human Protein Atlas · Open Targets · UniProt
Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.