SCUBA

PRSS3 — Serine protease 3

PRSS3 belongs to a gene co-expression module in 1 of 28 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.

PRSS3's module in each cell type

Cell typeModuleShares the module with
Goblet cellsEpithelial Differentiation Metabolism
Epithelial development
AKR1C3, BSG, GOLM1, PKM, TMEM45B, TMEM54, TSPAN8View in SCUBA

About the gene

SynonymsPRSS4, TRY3, TRY4
Chromosome9: 33750679-33799231
Predicted locationIntracellular, Secreted
Essential geneNo
Protein classEnzymes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins
Molecular functionHydrolase, Protease, Serine protease
Biological processDigestion

Function

Digestive protease that cleaves proteins preferentially after an Arg residue and has proteolytic activity toward Kunitz-type trypsin inhibitors.

Human Protein Atlas · Open Targets · UniProt

Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.