PTCRA — Pre T cell antigen receptor alpha
PTCRA belongs to a gene co-expression module in 1 of 28 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.
PTCRA's module in each cell type
| Cell type | Module | Shares the module with | |
|---|---|---|---|
| Hematopoietic progenitor cells | Platelet Biogenesis Myeloid development | CAVIN2, CCL5, CMTM5, F13A1, GNG11, GP9, MAP3K7CL, NRGN +6 more |
About the gene
| Synonyms | PT-ALPHA, PTA |
|---|---|
| Chromosome | 6: 42915989-42925838 |
| Predicted location | Membrane |
| Essential gene | No |
| Protein class | Predicted membrane proteins |
| Molecular function | Receptor |
Function
Component of the pre-T-cell receptor complex (composed of PTCRA, TCRB and the CD3 complex) that has a crucial role in early T- cell development, particularly alpha-beta T cell differentiation
Human Protein Atlas · Open Targets · UniProt
Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.