REP15 — RAB15 effector protein
REP15 belongs to a gene co-expression module in 1 of 28 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.
REP15's module in each cell type
| Cell type | Module | Shares the module with | |
|---|---|---|---|
| Goblet cells | Goblet Secretory Identity Mucus production & secretion | CREB3L1, ENTPD8, FKBP11, GNE, ITLN1, NPDC1, SH3BGRL3, SLC50A1 +4 more | View in SCUBA |
About the gene
| Synonyms | RAB15EP |
|---|---|
| Chromosome | 12: 27696447-27697596 |
| Predicted location | Intracellular |
| Essential gene | No |
| Protein class | Predicted intracellular proteins |
Function
Effector that interacts with Rab GTPases in their active form (GTP-bound) including RAB15, RAB3A-D and RAB34. Controls downstream signaling such as cell proliferation and cell migration. Also regulates transferrin receptor recycling from the endocytic recycling compartment
Human Protein Atlas · Open Targets · UniProt
Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.