NPDC1 — Neural proliferation, differentiation and control 1
NPDC1 belongs to a gene co-expression module in 6 of 28 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.
NPDC1's module in each cell type
| Cell type | Module | Shares the module with | |
|---|---|---|---|
| CD4⁺ T cells | mRNA stability regulation Immune regulation | APLP2, ARID5B, CARHSP1, GK, GLCCI1, GRAMD4, HIVEP1, METTL8 +12 more | View in SCUBA |
| Endothelial | Hypoxia-IFN Endothelial Endothelial cell development | BCAM, CRIP2, EPAS1, FES, HEG1, IFI27, IFITM1, LIMA1 +8 more | View in SCUBA |
| Gamma-delta T cells | Naïve T Cell State T cell maturation | ARL14EP, CCR2, CD27, CD28, CD40LG, CD82, CNN2, CPNE2 +19 more | |
| Glial cells | Enteric Glial Homeostasis Housekeeping | APOE, BCHE, CCND3, COL12A1, ENTPD2, FXYD6, PAQR6, PCSK1N +5 more | View in SCUBA |
| Goblet cells | Goblet Secretory Identity Mucus production & secretion | CREB3L1, ENTPD8, FKBP11, GNE, ITLN1, REP15, SH3BGRL3, SLC50A1 +4 more | View in SCUBA |
| Hematopoietic progenitor cells | Interferon Stimulated Inflammatory | BST2, EGFL7, IFITM3, LKAAEAR1, MGST3, PRDX1, VAMP5 |
About the gene
| Synonyms | CAB-, CAB1, DKFZp586J0523 |
|---|---|
| Chromosome | 9: 137039463-137046179 |
| Predicted location | Intracellular, Membrane |
| Essential gene | No |
| Protein class | Predicted intracellular proteins, Predicted membrane proteins |
Function
Suppresses oncogenic transformation in neural and non-neural cells and down-regulates neural cell proliferation. Might be involved in transcriptional regulation (By similarity)
Human Protein Atlas · Open Targets · UniProt
Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.