RIMOC1 — RAB7A interacting MON1-CCZ1 complex subunit 1
RIMOC1 belongs to a gene co-expression module in 1 of 28 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.
RIMOC1's module in each cell type
| Cell type | Module | Shares the module with | |
|---|---|---|---|
| Mucosal-associated invariant T cell | MAIT Effector Maturation T cell maturation | ASF1A, BET1, CRYZ, DAXX, ECI2, EOMES, FNTA, IRF3 +10 more |
About the gene
| Synonyms | C5orf51, LOC285636 |
|---|---|
| Chromosome | 5: 41904188-41921636 |
| Predicted location | Intracellular |
| Essential gene | No |
| Protein class | Predicted intracellular proteins |
| Biological process | Autophagy |
Function
Plays an important role in the removal of damaged mitochondria via mitophagy by controlling the stability and localization of RAB7A. Required for the recruitment of RAB7A and ATG9A vesicles to damaged mitochondria and promotes the stability of RAB7A by inhibiting its proteasomal degradation during mitophagy
Human Protein Atlas · Open Targets · UniProt
Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.