RIN2 — Ras and Rab interactor 2
RIN2 belongs to a gene co-expression module in 1 of 28 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.
RIN2's module in each cell type
| Cell type | Module | Shares the module with | |
|---|---|---|---|
| Enterocytes | Mature colonocyte metabolism Nutrient metabolism | ANXA4, ASS1, ATP1B3, BTNL3, CORO2A, HMCN2, MGAT4A, MOB3B +6 more | View in SCUBA |
About the gene
| Synonyms | RASSF4 |
|---|---|
| Chromosome | 20: 19757606-20002457 |
| Predicted location | Intracellular |
| Essential gene | No |
| Protein class | Disease related genes, Human disease related genes, Predicted intracellular proteins |
| Molecular function | GTPase activation |
| Biological process | Endocytosis |
Function
Ras effector protein. May function as an upstream activator and/or downstream effector for RAB5B in endocytic pathway. May function as a guanine nucleotide exchange (GEF) of RAB5B, required for activating the RAB5 proteins by exchanging bound GDP for free GTP
Human Protein Atlas · Open Targets · UniProt
Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.