MOB3B — MOB kinase activator 3B
MOB3B belongs to a gene co-expression module in 3 of 28 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.
MOB3B's module in each cell type
| Cell type | Module | Shares the module with | |
|---|---|---|---|
| CD19⁺ B cells | Adhesion/Migration migration & adhesion | ADAM28, ADAMTS6, ARHGAP24, ARHGAP5, CHPT1, CLMN, CMTR2, FCMR +11 more | View in SCUBA |
| Enterocytes | Mature colonocyte metabolism Nutrient metabolism | ANXA4, ASS1, ATP1B3, BTNL3, CORO2A, HMCN2, MGAT4A, MTUS1 +6 more | View in SCUBA |
| Macrophages | Innate Immune Dampening Innate immunity | DCAF6, ELL2, FGD4, FKBP5, IRAK3, MAP2K4, PACSIN2, PAPSS2 +10 more | View in SCUBA |
About the gene
| Synonyms | C9orf35, FLJ13204, MOB1D, MOBKL2B |
|---|---|
| Chromosome | 9: 27325209-27529814 |
| Predicted location | Intracellular |
| Essential gene | No |
| Protein class | Predicted intracellular proteins |
Function
Modulates LATS1 expression in the Hippo signaling pathway which plays a pivotal role in organ size control and tumor suppression by restricting proliferation and promoting apoptosis
Human Protein Atlas · Open Targets · UniProt
Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.