RNASEH2A — Ribonuclease H2 subunit A
RNASEH2A belongs to a gene co-expression module in 1 of 28 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.
RNASEH2A's module in each cell type
| Cell type | Module | Shares the module with | |
|---|---|---|---|
| Gamma-delta T cells | Mitotic Spindle Cell cycle | CAPRIN1, CDK5RAP2, CKAP5, CNTRL, DEK, DNMT1, FAM111A, GMPS +11 more |
About the gene
| Synonyms | AGS4, RNASEHI, RNHIA, RNHL |
|---|---|
| Chromosome | 19: 12806584-12813640 |
| Predicted location | Intracellular |
| Essential gene | No |
| Protein class | Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins |
| Molecular function | Endonuclease, Hydrolase, Nuclease |
Function
Catalytic subunit of RNase HII, an endonuclease that specifically degrades the RNA of RNA:DNA hybrids. Participates in DNA replication, possibly by mediating the removal of lagging-strand Okazaki fragment RNA primers during DNA replication. Mediates the excision of single ribonucleotides from DNA:RNA duplexes
Human Protein Atlas · Open Targets · UniProt
Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.