GMPS — Guanine monophosphate synthase
GMPS belongs to a gene co-expression module in 2 of 28 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.
GMPS's module in each cell type
| Cell type | Module | Shares the module with | |
|---|---|---|---|
| Gamma-delta T cells | Mitotic Spindle Cell cycle | CAPRIN1, CDK5RAP2, CKAP5, CNTRL, DEK, DNMT1, FAM111A, HADH +11 more | |
| Macrophages | Centrosome & DNA Repair Cell cycle | ANKRD13A, BRCA2, CASP2, CBX5, CCDC14, CEP152, CEP78, CKAP5 +34 more | View in SCUBA |
About the gene
| Synonyms | GATD7 |
|---|---|
| Chromosome | 3: 155870650-155944020 |
| Predicted location | Intracellular |
| Essential gene | Yes |
| Protein class | Disease related genes, Enzymes, Essential proteins, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins |
| Molecular function | Ligase |
| Biological process | GMP biosynthesis, Purine biosynthesis |
Function
Catalyzes the conversion of xanthine monophosphate (XMP) to GMP in the presence of glutamine and ATP through an adenyl-XMP intermediate
Human Protein Atlas · Open Targets · UniProt
Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.