CNTRL — Centriolin
CNTRL belongs to a gene co-expression module in 4 of 28 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.
CNTRL's module in each cell type
| Cell type | Module | Shares the module with | |
|---|---|---|---|
| CD4⁺ T cells | Chromatin regulation DNA/chromatin regulation | ANKRD11, BIRC6, EP300, FAM118A, GOLGA4, IRF2, KAT6A, MIER1 +12 more | View in SCUBA |
| Gamma-delta T cells | Mitotic Spindle Cell cycle | CAPRIN1, CDK5RAP2, CKAP5, DEK, DNMT1, FAM111A, GMPS, HADH +11 more | |
| Mucosal-associated invariant T cell | Lymphocyte Survival T cell maturation | ARHGEF3, BTN3A1, GIMAP8, ME2, PCMTD1, PRKACB, RSBN1L, SHPRH +4 more | |
| Neutrophils | S-G2-M Cell Cycle Cell cycle | ATAD2, CENPP, EZH2, LNPEP, MIS18BP1, RRM2, SMC4, TOPBP1 +1 more |
About the gene
| Synonyms | CEP1, CEP110 |
|---|---|
| Chromosome | 9: 121074660-121177729 |
| Predicted location | Intracellular |
| Essential gene | No |
| Protein class | Cancer-related genes, Disease related genes, Plasma proteins, Predicted intracellular proteins |
| Biological process | Cell cycle, Cell division |
Function
Involved in cell cycle progression and cytokinesis. During the late steps of cytokinesis, anchors exocyst and SNARE complexes at the midbody, thereby allowing secretory vesicle-mediated abscission
Human Protein Atlas · Open Targets · UniProt
Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.