DEK — DEK proto-oncogene

DEK belongs to a gene co-expression module in 8 of 28 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.

DEK's module in each cell type

Cell type	Module	Shares the module with
CD4⁺ T cells	Integrin Adhesion Migration migration & adhesion	ARAP2, ATF7IP, C4orf3, CLEC2B, COTL1, CTSH, DIAPH1, EML4 +11 more	View in SCUBA
Endothelial	Nuclear Transport Housekeeping	AAMDC, ANP32B, CBX5, CDK4, CKAP4, COMMD4, COQ2, CSE1L +18 more	View in SCUBA
Gamma-delta T cells	Mitotic Spindle Cell cycle	CAPRIN1, CDK5RAP2, CKAP5, CNTRL, DNMT1, FAM111A, GMPS, HADH +11 more
Goblet cells	Mitochondrial Chaperone Protein processing & ER	ANP32B, C1QBP, CACYBP, HSPD1, HSPE1, LDHB, LSM2, PA2G4	View in SCUBA
Lymphatic endothelial	Integrin Focal Adhesion migration & adhesion	APLP2, ATP5F1A, ATP5PB, ITGB1, LIMS1, MCFD2, NPC2, NUCKS1 +4 more	View in SCUBA
Macrophages	Replication Chromatin Assembly Cell cycle	ANP32B, CBX3, CDK4, COPS3, DNMT1, EMC8, EXOSC8, FDPS +22 more	View in SCUBA
Natural Killer cells	Chromatin Remodeling DNA regulation & transcription	ANP32E, CALM3, CBX5, COX8A, HMGB1, NUCB2, NUCKS1, PSIP1 +1 more	View in SCUBA
Neutrophils	Mitotic Spindle Cell cycle	ANP32B, ANP32E, H2AZ2, H4C3, HMGB1, HNRNPH1, HP1BP3, NUCKS1 +4 more

About the gene

Synonyms	D6S231E
Chromosome	6: 18223860-18264548
Predicted location	Intracellular
Essential gene	No
Protein class	Cancer-related genes, Disease related genes, Plasma proteins, Predicted intracellular proteins
Molecular function	Chromatin regulator, DNA-binding

Function

Involved in chromatin organization

Human Protein Atlas · Open Targets · UniProt

Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.