SCAI — Suppressor of cancer cell invasion
SCAI belongs to a gene co-expression module in 1 of 30 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.
SCAI's module in each cell type
| Cell type | Module | Shares the module with | |
|---|---|---|---|
| Colonocytes | DNA Damage Response Stress | ACSL4, AKNA, ALDH4A1, ATF7IP, ATM, BAIAP2, BCL11B, BCL9 +22 more | View in SCUBA |
About the gene
| Synonyms | C9orf126, FLJ36664, NET40 |
|---|---|
| Chromosome | 9: 124942608-125143528 |
| Predicted location | Intracellular |
| Essential gene | No |
| Protein class | Predicted intracellular proteins |
| Molecular function | Repressor, Signal transduction inhibitor |
| Biological process | Transcription, Transcription regulation |
Function
Tumor suppressor which functions to suppress MRTFA-induced SRF transcriptional activity. May function in the RHOA-DIAPH1 signal transduction pathway and regulate cell migration through transcriptional regulation of ITGB1
Human Protein Atlas · Open Targets · UniProt
Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.