SDC1 — Syndecan 1
SDC1 belongs to a gene co-expression module in 1 of 30 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.
SDC1's module in each cell type
| Cell type | Module | Shares the module with | |
|---|---|---|---|
| Colonocytes | Integrin Adhesion Signaling migration & adhesion | ARF1, C1GALT1, C1orf210, CCNI, CD164, CFL1, CMPK1, DIAPH1 +26 more | View in SCUBA |
About the gene
| Synonyms | CD138, SDC, SYND1, syndecan |
|---|---|
| Chromosome | 2: 20200797-20225433 |
| Predicted location | Intracellular, Membrane, Secreted |
| Essential gene | No |
| Protein class | Cancer-related genes, CD markers, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins, Transporters |
Function
Cell surface proteoglycan that contains both heparan sulfate and chondroitin sulfate and that links the cytoskeleton to the interstitial matrix (By similarity). Regulates exosome biogenesis in concert with SDCBP and PDCD6IP. Able to induce its own expression in dental mesenchymal cells and also in the neighboring dental epithelial cells via an MSX1-mediated pathway (By similarity)
Human Protein Atlas · Open Targets · UniProt
Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.