CD164 — CD164 molecule

CD164 belongs to a gene co-expression module in 10 of 28 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.

CD164's module in each cell type

Cell type	Module	Shares the module with
CD19⁺ B cells	B-cell activation B cell maturation	ADAM19, ARHGAP30, CD19, CD47, CLN8, CPEB4, ELK3, FNIP1 +15 more	View in SCUBA
CD4⁺ T cells	mRNA Processing RNA processing	ABI1, AGFG1, CCND3, CHMP2B, DBF4, GHITM, HNRNPL, LSM1 +9 more	View in SCUBA
CD8⁺ T cells	Gut Tissue Residency Gut residence	ALOX5AP, C4orf3, CAPN2, CD3D, CD7, CD99, CLIC3, ID2 +9 more	View in SCUBA
Enterocytes	Lysosomal/ferritin housekeeping Housekeeping	APLP2, CRIP1, CST3, EDF1, FTH1, FTL, GPA33, ITM2B +5 more	View in SCUBA
Gamma-delta T cells	Antiviral ISG Response Inflammation	ACTR1A, ATRX, CYTH4, FGD3, GIT2, LASP1, PARP10, RGS3 +6 more
Hematopoietic progenitor cells	HSC Quiescence Program Stemness	ADGRG6, AVP, CCDC175, CDH7, CHRM3, EGLN3, HEMGN, HLF +7 more
Innate lymphoid cells	Protein Biogenesis & Import Protein processing & ER	ANAPC16, ATP6AP2, COMMD6, EEF1D, KLRB1, NACA, PFDN5, S100A4 +6 more	View in SCUBA
Macrophages	ER Membrane Homeostasis Housekeeping	ATP6V1A, BNIP2, CANX, CAPZA1, CMTM6, COPB1, EXOC5, GFM1 +18 more	View in SCUBA
Mucosal-associated invariant T cell	Nuclear regulatory housekeeping Housekeeping	ATXN2, BAZ1B, CCDC90B, CREB1, GIGYF2, HELB, HNRNPA2B1, PHIP +6 more
Smooth muscle cells	Endolysosomal Trafficking Housekeeping	ARPC3, FKBP1A, IFITM3, LAMTOR1, NDFIP1, RAB5C, RABAC1, TMEM50A	View in SCUBA

About the gene

Synonyms	DFNA66, MGC-24, MUC-24
Chromosome	6: 109366514-109382467
Predicted location	Intracellular, Membrane
Essential gene	No
Protein class	CD markers, Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins
Biological process	Cell adhesion, Myogenesis

Function

Sialomucin that may play a key role in hematopoiesis by facilitating the adhesion of CD34(+) cells to the stroma and by negatively regulating CD34(+)CD38(lo/-) cell proliferation. Modulates the migration of umbilical cord blood CD133+ cells and this is mediated through the CXCL12/CXCR4 axis. May play an important role in prostate cancer metastasis and the infiltration of bone marrow by cancer cells. Promotes myogenesis by enhancing CXCR4-dependent cell motility. Positively regulates myoblast migration and promotes myoblast fusion into myotubes (By similarity).

Human Protein Atlas · Open Targets · UniProt

Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.