SEMA3A — Semaphorin 3A
SEMA3A belongs to a gene co-expression module in 1 of 28 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.
SEMA3A's module in each cell type
| Cell type | Module | Shares the module with | |
|---|---|---|---|
| Fibroblasts | Intestinal Fibroblast Identity Developmental | ABR, AFF3, ATP8A1, ATP9A, CAMK4, DSE, ENPP2, GLP2R +7 more | View in SCUBA |
About the gene
| Synonyms | coll-1, Hsema-I, SEMA1, SEMAD, SemD |
|---|---|
| Chromosome | 7: 83955777-84492724 |
| Predicted location | Secreted |
| Essential gene | No |
| Protein class | Disease related genes, Human disease related genes, Plasma proteins, Predicted secreted proteins |
| Molecular function | Developmental protein |
| Biological process | Differentiation, Neurogenesis |
Function
Involved in the development of the olfactory system and in neuronal control of puberty. Induces the collapse and paralysis of neuronal growth cones. Could serve as a ligand that guides specific growth cones by a motility-inhibiting mechanism. Binds to the complex neuropilin-1/plexin-1
Human Protein Atlas · Open Targets · UniProt
Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.