SCUBA

SEPTIN11 — Septin 11

SEPTIN11 belongs to a gene co-expression module in 1 of 28 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.

SEPTIN11's module in each cell type

Cell typeModuleShares the module with
Hematopoietic progenitor cellsCytoskeletal Remodeling
Cytoskeletal
AHNAK, ANXA1, ATP2B1, DPYSL3, FHL1, IDS, MBOAT7, MTURN +5 more

About the gene

SynonymsFLJ10849, SEPT11
Chromosome4: 76949751-77040384
Predicted locationIntracellular
Essential geneNo
Protein classDisease related genes, Plasma proteins, Predicted intracellular proteins
Biological processCell cycle, Cell division

Function

Filament-forming cytoskeletal GTPase. May play a role in cytokinesis (Potential). May play a role in the cytoarchitecture of neurons, including dendritic arborization and dendritic spines, and in GABAergic synaptic connectivity (By similarity). During Listeria monocytogenes infection, not required for the bacterial entry process, but restricts its efficacy.

Human Protein Atlas · Open Targets · UniProt

Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.