DPYSL3 — Dihydropyrimidinase like 3
DPYSL3 belongs to a gene co-expression module in 4 of 28 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.
DPYSL3's module in each cell type
| Cell type | Module | Shares the module with | |
|---|---|---|---|
| Fibroblasts | Wnt-Niche Fibroblast Developmental | AHNAK, AHNAK2, AKAP12, CELF2, CYSLTR1, DST, GAS6, HSPG2 +10 more | View in SCUBA |
| Glial cells | Glial Neuroprotective Response Neroprotection | ANXA4, CYB5A, DRAP1, FADS2, IGFBP4, MDK, NBDY, NDUFB2 +4 more | View in SCUBA |
| Hematopoietic progenitor cells | Cytoskeletal Remodeling Cytoskeletal | AHNAK, ANXA1, ATP2B1, FHL1, IDS, MBOAT7, MTURN, PBXIP1 +5 more | |
| Lymphatic endothelial | Actin Cytoskeletal Scaffold Cytoskeletal | CCDC102B, CCND3, DAAM1, EPB41L2, GOLM2, GPATCH2, KLHL4, PPFIBP1 +1 more | View in SCUBA |
About the gene
| Synonyms | CRMP4, DRP-3, ULIP |
|---|---|
| Chromosome | 5: 147390808-147510068 |
| Predicted location | Intracellular |
| Essential gene | No |
| Protein class | Predicted intracellular proteins |
Function
Necessary for signaling by class 3 semaphorins and subsequent remodeling of the cytoskeleton. Plays a role in axon guidance, neuronal growth cone collapse and cell migration (By similarity)
Human Protein Atlas · Open Targets · UniProt
Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.