SHMT1 — Serine hydroxymethyltransferase 1
SHMT1 belongs to a gene co-expression module in 2 of 28 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.
SHMT1's module in each cell type
| Cell type | Module | Shares the module with | |
|---|---|---|---|
| Gamma-delta T cells | Basal Lipid Metabolism Housekeeping | ACOT7, ADCY3, AHCY, CLN6, DENND6B, FANCL, MGLL, MPST +6 more | |
| Monocytes | IL-18 Inflammasome Response Inflammatory | CTTNBP2, DEPTOR, EPS8, IL18, LHFPL6, ME1, NPL, RNF141 | View in SCUBA |
About the gene
| Synonyms | cSHMT, MGC15229, MGC24556, SHMT |
|---|---|
| Chromosome | 17: 18327860-18363563 |
| Predicted location | Intracellular |
| Essential gene | No |
| Protein class | Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins |
| Molecular function | Transferase |
| Biological process | One-carbon metabolism |
Function
Interconversion of serine and glycine.
Human Protein Atlas · Open Targets · UniProt
Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.