SIL1 — SIL1 nucleotide exchange factor
SIL1 belongs to a gene co-expression module in 1 of 30 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.
SIL1's module in each cell type
| Cell type | Module | Shares the module with | |
|---|---|---|---|
| Colonocytes | ER Glycoprotein Folding Protein processing & ER | ABLIM1, ADAM15, ARHGAP32, CYB561, EML2, GMDS, GMPPB, GOLM1 +20 more | View in SCUBA |
About the gene
| Synonyms | BAP, MSS, ULG5 |
|---|---|
| Chromosome | 5: 138946724-139293557 |
| Predicted location | Intracellular |
| Essential gene | No |
| Protein class | Disease related genes, Human disease related genes, Predicted intracellular proteins |
| Biological process | Protein transport, Translocation, Transport |
Function
Required for protein translocation and folding in the endoplasmic reticulum (ER). Functions as a nucleotide exchange factor for the ER lumenal chaperone HSPA5
Human Protein Atlas · Open Targets · UniProt
Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.