SULT1A2 — Sulfotransferase family 1A member 2
SULT1A2 belongs to a gene co-expression module in 1 of 30 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.
SULT1A2's module in each cell type
| Cell type | Module | Shares the module with | |
|---|---|---|---|
| Colonocytes | Brush Border Cytoskeleton Cytoskeletal | ACOX1, ALDH18A1, CLIP2, DDAH2, ESPN, MAST2, MEP1A, MYLK +14 more | View in SCUBA |
About the gene
| Synonyms | HAST4, STP2 |
|---|---|
| Chromosome | 16: 28591943-28597050 |
| Predicted location | Intracellular |
| Essential gene | No |
| Protein class | Enzymes, Metabolic proteins, Predicted intracellular proteins |
| Molecular function | Transferase |
| Biological process | Catecholamine metabolism, Lipid metabolism, Steroid metabolism |
Function
Sulfotransferase that utilizes 3'-phospho-5'-adenylyl sulfate (PAPS) as sulfonate donor to catalyze the sulfate conjugation of catecholamines, phenolic drugs and neurotransmitters. Is also responsible for the sulfonation and activation of minoxidil. Mediates the metabolic activation of carcinogenic N-hydroxyarylamines to DNA binding products and could so participate as modulating factor of cancer risk
Human Protein Atlas · Open Targets · UniProt
Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.