ALDH18A1 — Aldehyde dehydrogenase 18 family member A1
ALDH18A1 belongs to a gene co-expression module in 1 of 28 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.
ALDH18A1's module in each cell type
| Cell type | Module | Shares the module with | |
|---|---|---|---|
| Enterocytes | PPARA/FXR fatty acid oxidation Lipid metabolism | ANO10, CPT1A, DGKD, FAT1, FMO5, NDRG1, NR1H4, PPARA +4 more | View in SCUBA |
About the gene
| Synonyms | GSAS, P5CS, PYCS, SPG9 |
|---|---|
| Chromosome | 10: 95605941-95656711 |
| Predicted location | Intracellular |
| Essential gene | No |
| Protein class | Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins |
| Molecular function | Kinase, Multifunctional enzyme, Oxidoreductase, Transferase |
| Biological process | Amino-acid biosynthesis, Proline biosynthesis |
Function
Bifunctional enzyme that converts glutamate to glutamate 5- semialdehyde, an intermediate in the biosynthesis of proline, ornithine and arginine.
Human Protein Atlas · Open Targets · UniProt
Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.