CLIP2 — CAP-Gly domain containing linker protein 2
CLIP2 belongs to a gene co-expression module in 2 of 28 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.
CLIP2's module in each cell type
| Cell type | Module | Shares the module with | |
|---|---|---|---|
| CD19⁺ B cells | B cell activation BCR/AP1/NFKb pathway | ADGRG5, BCAR3, CD86, CNOT2, CTSH, FAS, GABARAPL2, GPR137B +7 more | View in SCUBA |
| Macrophages | ER Stress Response Stress | ARHGEF12, ATXN7, BTBD7, CD2AP, DAPK1, DST, ERN1, ERO1B +14 more | View in SCUBA |
About the gene
| Synonyms | CLIP, CLIP-115, CYLN2, KIAA0291, WBSCR3, WBSCR4, WSCR3, WSCR4 |
|---|---|
| Chromosome | 7: 74289407-74405935 |
| Predicted location | Intracellular |
| Essential gene | No |
| Protein class | Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins |
Function
Seems to link microtubules to dendritic lamellar body (DLB), a membranous organelle predominantly present in bulbous dendritic appendages of neurons linked by dendrodendritic gap junctions. May operate in the control of brain-specific organelle translocations (By similarity)
Human Protein Atlas · Open Targets · UniProt
Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.