TBC1D17 — TBC1 domain family member 17
TBC1D17 belongs to a gene co-expression module in 1 of 28 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.
TBC1D17's module in each cell type
| Cell type | Module | Shares the module with | |
|---|---|---|---|
| Innate lymphoid cells | Transcriptional Activation DNA regulation & transcription | AKIRIN1, CHORDC1, FAM133B, FAM53C, GOLGB1, GTF2B, IDI1, MORF4L2 +9 more | View in SCUBA |
About the gene
| Synonyms | FLJ12168 |
|---|---|
| Chromosome | 19: 49877666-49888750 |
| Predicted location | Intracellular |
| Essential gene | No |
| Protein class | Predicted intracellular proteins |
| Molecular function | GTPase activation |
| Biological process | Autophagy, Protein transport, Transport |
Function
Probable RAB GTPase-activating protein that inhibits RAB8A/B function. Reduces Rab8 recruitment to tubules emanating from the endocytic recycling compartment (ERC) and inhibits Rab8-mediated endocytic trafficking, such as that of transferrin receptor (TfR). Involved in regulation of autophagy
Human Protein Atlas · Open Targets · UniProt
Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.