TNFSF15 — TNF superfamily member 15
TNFSF15 belongs to a gene co-expression module in 1 of 30 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.
TNFSF15's module in each cell type
| Cell type | Module | Shares the module with | |
|---|---|---|---|
| Colonocytes | DNA Damage Response Stress | ACSL4, AKNA, ALDH4A1, ATF7IP, ATM, BAIAP2, BCL11B, BCL9 +22 more | View in SCUBA |
About the gene
| Synonyms | MGC129934, MGC129935, TL1, TL1A, VEGI, VEGI192A |
|---|---|
| Chromosome | 9: 114784652-114806039 |
| Predicted location | Intracellular, Secreted |
| Essential gene | No |
| Protein class | Human disease related genes, Predicted intracellular proteins, Predicted secreted proteins |
| Molecular function | Cytokine |
Function
Receptor for TNFRSF25 and TNFRSF6B. Mediates activation of NF-kappa-B. Inhibits vascular endothelial growth and angiogenesis (in vitro). Promotes activation of caspases and apoptosis.
Human Protein Atlas · Open Targets · UniProt
Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.