TPSB2 — Tryptase beta 2
TPSB2 belongs to a gene co-expression module in 1 of 28 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.
TPSB2's module in each cell type
| Cell type | Module | Shares the module with | |
|---|---|---|---|
| Hematopoietic progenitor cells | Mast Cell Basophil Granulocyte development | ENPP3, HPGD, IL1RL1, ITGB8, KRT1, NDFIP2, SLC18A2, TPSD1 +1 more |
About the gene
| Chromosome | 16: 1227272-1230184 |
|---|---|
| Predicted location | Secreted |
| Essential gene | No |
| Protein class | Enzymes, Metabolic proteins, Predicted secreted proteins |
| Molecular function | Hydrolase, Protease, Serine protease |
Function
Tryptase is the major neutral protease present in mast cells and is secreted upon the coupled activation-degranulation response of this cell type. May play a role in innate immunity.
Human Protein Atlas · Open Targets · UniProt
Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.