TRIL — TLR4 interactor with leucine rich repeats
TRIL belongs to a gene co-expression module in 1 of 28 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.
TRIL's module in each cell type
| Cell type | Module | Shares the module with | |
|---|---|---|---|
| Fibroblasts | CYGB+ Quiescent Fibroblast Housekeeping | CCND1, CYGB, FARP1, FGFR4, FXYD5, NCAM1, NEGR1, NOVA1 +5 more | View in SCUBA |
About the gene
| Synonyms | KIAA0644 |
|---|---|
| Chromosome | 7: 28953358-28958330 |
| Predicted location | Membrane |
| Essential gene | No |
| Protein class | Predicted membrane proteins |
| Biological process | Immunity, Inflammatory response, Innate immunity |
Function
Component of the TLR4 signaling complex. Mediates the innate immune response to bacterial lipopolysaccharide (LPS) leading to cytokine secretion
Human Protein Atlas · Open Targets · UniProt
Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.