NCAM1 — Neural cell adhesion molecule 1
NCAM1 belongs to a gene co-expression module in 5 of 28 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.
NCAM1's module in each cell type
| Cell type | Module | Shares the module with | |
|---|---|---|---|
| Fibroblasts | CYGB+ Quiescent Fibroblast Housekeeping | CCND1, CYGB, FARP1, FGFR4, FXYD5, NEGR1, NOVA1, PDK4 +5 more | View in SCUBA |
| Gamma-delta T cells | NK-like Mature gd-T cytotoxicity | ABHD2, ATG9A, CEP78, HAVCR2, HSH2D, IFIT2, ITGAX, KIR2DL1 +14 more | |
| Glial cells | Glial Adhesion Cytoskeletal migration & adhesion | AKAP9, COL21A1, DOCK5, EPB41L2, KIAA1217, LTBP3, RALGPS2, SCN7A +1 more | View in SCUBA |
| Innate lymphoid cells | NK JAK3 Signaling activation | ANKRD44, APLP2, ATP8B4, CALCOCO2, ERLEC1, FLOT1, FUT8, FYCO1 +10 more | View in SCUBA |
| Mucosal-associated invariant T cell | Cytoskeletal Migration migration & adhesion | CHST11, HDAC9, MGAT5, NCOA2, PITPNC1, RASA2, SSH2 |
About the gene
| Synonyms | CD56, NCAM |
|---|---|
| Chromosome | 11: 112961247-113278436 |
| Predicted location | Intracellular, Membrane, Secreted |
| Essential gene | No |
| Protein class | Cancer-related genes, CD markers, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins, Transporters |
| Molecular function | Host cell receptor for virus entry, Receptor |
| Biological process | Cell adhesion, Host-virus interaction |
Function
This protein is a cell adhesion molecule involved in neuron- neuron adhesion, neurite fasciculation, outgrowth of neurites, etc. (Microbial infection) Acts as a receptor for rabies virus. (Microbial infection) Acts as a receptor for Zika virus
Human Protein Atlas · Open Targets · UniProt
Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.