TRNP1 — TMF1 regulated nuclear protein 1
TRNP1 belongs to a gene co-expression module in 1 of 28 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.
TRNP1's module in each cell type
| Cell type | Module | Shares the module with | |
|---|---|---|---|
| Smooth muscle cells | SMC Phenotype Regulation Development | ARHGAP42, BMPR2, CTXN1, EFR3A, FAM20B, HACD4, INPP5A, OSBPL1A +5 more | View in SCUBA |
About the gene
| Synonyms | C1orf225, TRNP |
|---|---|
| Chromosome | 1: 26993692-27000886 |
| Predicted location | Intracellular |
| Essential gene | No |
| Protein class | Predicted intracellular proteins |
| Molecular function | Developmental protein, DNA-binding |
| Biological process | Cell cycle, Neurogenesis, Transcription, Transcription regulation |
Function
DNA-binding factor that regulates the expression of a subset of genes and plays a key role in tangential, radial, and lateral expansion of the brain neocortex. Regulates neural stem cells proliferation and the production of intermediate neural progenitors and basal radial glial cells affecting the process of cerebral cortex gyrification. May control the proliferation rate of cells by regulating their progression through key cell-cycle transition points (By similarity)
Human Protein Atlas · Open Targets · UniProt
Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.