SCUBA

UTP6 — UTP6 small subunit processome component

UTP6 belongs to a gene co-expression module in 1 of 28 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.

UTP6's module in each cell type

Cell typeModuleShares the module with
Gamma-delta T cellsUbiquitin Protein Quality
Protein processing & ER
CHMP7, CLCN3, EDEM3, GART, GOPC, HERC4, KRIT1, LRIF1 +13 more

About the gene

SynonymsC17orf40, HCA66
Chromosome17: 31860904-31901708
Predicted locationIntracellular
Essential geneYes
Protein classEssential proteins, Predicted intracellular proteins
Biological processrRNA processing

Function

Part of the small subunit (SSU) processome, first precursor of the small eukaryotic ribosomal subunit. During the assembly of the SSU processome in the nucleolus, many ribosome biogenesis factors, an RNA chaperone and ribosomal proteins associate with the nascent pre- rRNA and work in concert to generate RNA folding, modifications, rearrangements and cleavage as well as targeted degradation of pre- ribosomal RNA by the RNA exosome. Involved in nucleolar processing of pre-18S ribosomal RNA

Human Protein Atlas · Open Targets · UniProt

Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.