VNN2 — Vanin 2
VNN2 belongs to a gene co-expression module in 2 of 28 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.
VNN2's module in each cell type
| Cell type | Module | Shares the module with | |
|---|---|---|---|
| Fibroblasts | COL13A1+ Deep Fibroblast ECM production | APOC1, BMPER, COL13A1, CSF1, GPR63, GPX3, GRIA3, HAAO +6 more | View in SCUBA |
| Neutrophils | Mature Neutrophil Identity Developmental | JAML, LRP10, LRRK2, MME, MMP25, MSL1, R3HDM4, SELPLG +1 more |
About the gene
| Synonyms | FOAP-4, GPI-80 |
|---|---|
| Chromosome | 6: 132743870-132763459 |
| Predicted location | Intracellular, Membrane |
| Essential gene | No |
| Protein class | Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins |
| Molecular function | Hydrolase |
Function
Amidohydrolase that hydrolyzes specifically one of the carboamide linkages in D-pantetheine thus recycling pantothenic acid (vitamin B5) and releasing cysteamine. Involved in the thymus homing of bone marrow cells. May regulate beta-2 integrin- mediated cell adhesion, migration and motility of neutrophil
Human Protein Atlas · Open Targets · UniProt
Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.