COL13A1 — Collagen type XIII alpha 1 chain
COL13A1 belongs to a gene co-expression module in 2 of 28 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.
COL13A1's module in each cell type
| Cell type | Module | Shares the module with | |
|---|---|---|---|
| Endothelial | Angiogenic Endothelial Identity Endothelial cell development | ADAMTSL2, ARHGAP29, CTNNB1, EDIL3, EML1, ETS1, EXOC3L1, FHOD1 +14 more | View in SCUBA |
| Fibroblasts | COL13A1+ Deep Fibroblast ECM production | APOC1, BMPER, CSF1, GPR63, GPX3, GRIA3, HAAO, KLRF1 +6 more | View in SCUBA |
About the gene
| Chromosome | 10: 69801880-69964275 |
|---|---|
| Predicted location | Intracellular, Membrane |
| Essential gene | No |
| Protein class | Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins |
| Molecular function | Developmental protein, Heparin-binding |
| Biological process | Cell adhesion, Differentiation, Osteogenesis |
Function
Involved in cell-matrix and cell-cell adhesion interactions that are required for normal development. May participate in the linkage between muscle fiber and basement membrane. May play a role in endochondral ossification of bone and branching morphogenesis of lung. Binds heparin. At neuromuscular junctions, may play a role in acetylcholine receptor clustering.
Human Protein Atlas · Open Targets · UniProt
Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.