AMPD3 — Adenosine monophosphate deaminase 3
AMPD3 belongs to a gene co-expression module in 2 of 28 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.
AMPD3's module in each cell type
| Cell type | Module | Shares the module with | |
|---|---|---|---|
| Fibroblasts | Fibroblast Niche Identity Developmental | ALKAL2, CHST1, CNTFR, COL4A6, CTTNBP2, CXCR4, DDHD1, EDAR +10 more | View in SCUBA |
| Macrophages | Hypoxia Stress Response Stress | ACE, APP, ASPH, BCAT1, BEX3, BHLHE41, BNIP3, CAPN2 +34 more | View in SCUBA |
About the gene
| Chromosome | 11: 10308313-10507579 |
|---|---|
| Predicted location | Intracellular |
| Essential gene | No |
| Protein class | Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins |
| Molecular function | Hydrolase |
| Biological process | Nucleotide metabolism |
Function
AMP deaminase plays a critical role in energy metabolism
Human Protein Atlas · Open Targets · UniProt
Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.