ARHGAP27 — Rho GTPase activating protein 27
ARHGAP27 belongs to a gene co-expression module in 2 of 28 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.
ARHGAP27's module in each cell type
| Cell type | Module | Shares the module with | |
|---|---|---|---|
| Hematopoietic progenitor cells | Lymphoid-Primed Progenitor Lymphcyte development | CD22, COBLL1, LILRB2, LTB, PACSIN1, S100Z, SH3TC1, SLC2A5 +4 more | |
| Macrophages | Mixed Regulatory Signaling Housekeeping | ADAP2, AKAP11, ARHGAP17, BLTP2, BLTP3A, C2CD2L, COG2, DELE1 +30 more | View in SCUBA |
About the gene
| Synonyms | CAMGAP1, FLJ43547, SH3D20, SH3P20 |
|---|---|
| Chromosome | 17: 45393902-45434421 |
| Predicted location | Intracellular |
| Essential gene | No |
| Protein class | Predicted intracellular proteins |
| Molecular function | GTPase activation |
| Biological process | Endocytosis |
Function
Rho GTPase-activating protein which may be involved in clathrin-mediated endocytosis. GTPase activators for the Rho-type GTPases act by converting them to an inactive GDP-bound state. Has activity toward CDC42 and RAC1 (By similarity)
Human Protein Atlas · Open Targets · UniProt
Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.