ARHGAP31 — Rho GTPase activating protein 31
ARHGAP31 belongs to a gene co-expression module in 1 of 28 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.
ARHGAP31's module in each cell type
| Cell type | Module | Shares the module with | |
|---|---|---|---|
| Endothelial | EC Barrier Integrity Endothelial cell development | ABCB1, ADCY4, AQP3, CRYBG3, EPS8, FGR, FRYL, GULP1 +14 more | View in SCUBA |
About the gene
| Synonyms | CDGAP |
|---|---|
| Chromosome | 3: 119294383-119420714 |
| Predicted location | Intracellular |
| Essential gene | No |
| Protein class | Disease related genes, Human disease related genes, Predicted intracellular proteins |
| Molecular function | GTPase activation |
Function
Functions as a GTPase-activating protein (GAP) for RAC1 and CDC42. Required for cell spreading, polarized lamellipodia formation and cell migration.
Human Protein Atlas · Open Targets · UniProt
Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.