SCUBA

ARMC9 — Armadillo repeat containing 9

ARMC9 belongs to a gene co-expression module in 1 of 28 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.

ARMC9's module in each cell type

Cell typeModuleShares the module with
MacrophagesNRF2 Oxidative Stress
Stress
ACOT9, AHRR, BASP1, CARD19, CCDC71L, CD226, CLDND1, CTNNBL1 +27 moreView in SCUBA

About the gene

SynonymsARM, FLJ12584, KIAA1868, KU-MEL-1
Chromosome2: 231198546-231376848
Predicted locationIntracellular
Essential geneNo
Protein classDisease related genes, Human disease related genes, Predicted intracellular proteins
Biological processCilium biogenesis/degradation

Function

Involved in ciliogenesis. It is required for appropriate acetylation and polyglutamylation of ciliary microtubules, and regulation of cilium length. Acts as a positive regulator of hedgehog (Hh)signaling (By similarity). May participate in the trafficking and/or retention of GLI2 and GLI3 proteins at the ciliary tip (By similarity).

Human Protein Atlas · Open Targets · UniProt

Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.