CARD19 — Caspase recruitment domain family member 19
CARD19 belongs to a gene co-expression module in 2 of 28 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.
CARD19's module in each cell type
| Cell type | Module | Shares the module with | |
|---|---|---|---|
| Macrophages | NRF2 Oxidative Stress Stress | ACOT9, AHRR, ARMC9, BASP1, CCDC71L, CD226, CLDND1, CTNNBL1 +27 more | View in SCUBA |
| Monocytes | Innate Immune Transcription Innate immunity | COG3, CSNK1E, ELF4, EXTL3, PCIF1, RBM38, SMIM3, ZFYVE9 | View in SCUBA |
About the gene
| Synonyms | bA370F5.1, BinCARD, C9orf89, MGC11115 |
|---|---|
| Chromosome | 9: 93096217-93113283 |
| Predicted location | Membrane |
| Essential gene | No |
| Protein class | Predicted membrane proteins |
Function
Plays a role in inhibiting the effects of BCL10-induced activation of NF-kappa-B. May inhibit the phosphorylation of BCL10 in a CARD-dependent manner
Human Protein Atlas · Open Targets · UniProt
Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.