ATRN — Attractin
ATRN belongs to a gene co-expression module in 2 of 28 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.
ATRN's module in each cell type
| Cell type | Module | Shares the module with | |
|---|---|---|---|
| Enterocytes | Long-gene nuclear transcripts Technical artifact | ABO, AIG1, CACNB2, FOXN3, IMMP2L, KCNJ3, PLA2R1, TIAM2 | View in SCUBA |
| Macrophages | Post-transcriptional Regulation Housekeeping | AKAP10, ATF7IP, ATXN2, BAZ2B, BLTP1, BRWD1, CELF2, CEP350 +34 more | View in SCUBA |
About the gene
| Synonyms | DPPT-L, MGCA |
|---|---|
| Chromosome | 20: 3471018-3651118 |
| Predicted location | Membrane, Secreted |
| Essential gene | No |
| Protein class | Plasma proteins, Predicted membrane proteins, Predicted secreted proteins |
| Molecular function | Receptor |
| Biological process | Inflammatory response |
Function
Involved in the initial immune cell clustering during inflammatory response and may regulate chemotactic activity of chemokines. May play a role in melanocortin signaling pathways that regulate energy homeostasis and hair color. Low-affinity receptor for agouti (By similarity). Has a critical role in normal myelination in the central nervous system (By similarity).
Human Protein Atlas · Open Targets · UniProt
Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.