BLTP1 — Bridge-like lipid transfer protein family member 1
BLTP1 belongs to a gene co-expression module in 3 of 28 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.
BLTP1's module in each cell type
| Cell type | Module | Shares the module with | |
|---|---|---|---|
| Gamma-delta T cells | Chromatin Epigenetic Regulation DNA/chromatin regulation | ACIN1, ASH1L, BDP1, CLTC, EPS15, EXOC2, FAM120B, GATAD2B +24 more | |
| Macrophages | Post-transcriptional Regulation Housekeeping | AKAP10, ATF7IP, ATRN, ATXN2, BAZ2B, BRWD1, CELF2, CEP350 +34 more | View in SCUBA |
| Neutrophils | Apoptotic Neutrophil Program Developmental | ANO10, APAF1, ARFGEF1, ATF7IP, CEP350, FAR2, FBXW2, HIPK2 +5 more |
About the gene
| Synonyms | FLJ21404, FSA, KIAA1109, KIAA1371, Tweek |
|---|---|
| Chromosome | 4: 122152331-122364167 |
| Predicted location | Intracellular, Membrane |
| Essential gene | No |
| Protein class | Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins |
Function
Tube-forming lipid transport protein which provides phosphatidylethanolamine for glycosylphosphatidylinositol (GPI) anchor synthesis in the endoplasmic reticulum (Probable). Plays a role in endosomal trafficking and endosome recycling. Also involved in the actin cytoskeleton and cilia structural dynamics. Acts as a regulator of phagocytosis.
Human Protein Atlas · Open Targets · UniProt
Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.