SCUBA

C1RL — Complement C1r subcomponent like

C1RL belongs to a gene co-expression module in 1 of 28 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.

C1RL's module in each cell type

Cell typeModuleShares the module with
Mucosal-associated invariant T cellChromatin Remodeling
DNA/chromatin regulation
BAZ2B, CD2AP, GIT2, KIF5B, MIA2, RIF1, SPAG9, SUPT16H +1 more

About the gene

SynonymsC1r-LP, C1RL1
Chromosome12: 7089587-7109238
Predicted locationIntracellular, Secreted
Essential geneNo
Protein classEnzymes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins
Molecular functionHydrolase, Protease, Serine protease
Biological processComplement pathway, Immunity, Innate immunity

Function

Mediates the proteolytic cleavage of HP/haptoglobin in the endoplasmic reticulum.

Human Protein Atlas · Open Targets · UniProt

Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.