GIT2 — GIT ArfGAP 2
GIT2 belongs to a gene co-expression module in 6 of 28 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.
GIT2's module in each cell type
| Cell type | Module | Shares the module with | |
|---|---|---|---|
| CD4⁺ T cells | Immune regulation Immune regulation | DENND1B, FAM111A, GOLGA8A, LPIN1, NLRC3, PPP2R5C, PSD4, RUFY3 +5 more | View in SCUBA |
| Endothelial | EC Quiescence Identity Endothelial cell development | ABCC4, ARHGAP5, C1orf115, ENPP4, FAM107A, IFNAR2, LRRFIP1, MSI2 +8 more | View in SCUBA |
| Gamma-delta T cells | Antiviral ISG Response Inflammation | ACTR1A, ATRX, CD164, CYTH4, FGD3, LASP1, PARP10, RGS3 +6 more | |
| Macrophages | Chromatin Transcriptional Regulation Housekeeping | AGO1, ARID1A, CARD8, CEPT1, CLOCK, CPSF7, CTNND1, DCAF10 +19 more | View in SCUBA |
| Mucosal-associated invariant T cell | Chromatin Remodeling DNA/chromatin regulation | BAZ2B, C1RL, CD2AP, KIF5B, MIA2, RIF1, SPAG9, SUPT16H +1 more | |
| Neutrophils | JAK-MAPK Signaling Inflammatory | CELF2, ENTPD1, JAK2, MAPK1, MBNL1, SLMAP, SPTLC2, TLE4 +1 more |
About the gene
| Synonyms | KIAA0148, PKL |
|---|---|
| Chromosome | 12: 109929804-109996389 |
| Predicted location | Intracellular |
| Essential gene | No |
| Protein class | Plasma proteins, Predicted intracellular proteins |
| Molecular function | GTPase activation |
Function
GTPase-activating protein for ADP ribosylation factor family members, including ARF1
Human Protein Atlas · Open Targets · UniProt
Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.