SCUBA

C2CD5 — C2 calcium dependent domain containing 5

C2CD5 belongs to a gene co-expression module in 1 of 28 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.

C2CD5's module in each cell type

Cell typeModuleShares the module with
MacrophagesMITF Lysosomal Program
Lysosomal & pahgocytosis
ABHD3, ANKRD44, ARSB, CERS6, CHST11, CNST, DCTN4, FBXL20 +25 moreView in SCUBA

About the gene

SynonymsCDP138, KIAA0528
Chromosome12: 22448583-22544546
Predicted locationIntracellular
Essential geneNo
Protein classPredicted intracellular proteins
Biological processProtein transport, Transport

Function

Required for insulin-stimulated glucose transport and glucose transporter SLC2A4/GLUT4 translocation from intracellular glucose storage vesicle (GSV) to the plasma membrane (PM) in adipocytes. Binds phospholipid membranes in a calcium-dependent manner and is necessary for the optimal membrane fusion between SLC2A4/GLUT4 GSV and the PM

Human Protein Atlas · Open Targets · UniProt

Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.