ANKRD44 — Ankyrin repeat domain 44
ANKRD44 belongs to a gene co-expression module in 7 of 28 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.
ANKRD44's module in each cell type
| Cell type | Module | Shares the module with | |
|---|---|---|---|
| CD19⁺ B cells | B cell activation signaling B cell maturation | BLK, BTN3A2, EVI2B, GAPT, GPSM3, LBH, LTB, LY86 +9 more | View in SCUBA |
| Gamma-delta T cells | Interferon Antiviral Response Inflammation | DDX17, DDX60L, IARS2, KIAA0319L, KRBOX5, LZIC, MIA2, PIK3CD +14 more | |
| Hematopoietic progenitor cells | Lymphoid Progenitor TFs Lymphcyte development | ADAM28, AFF3, CYFIP2, CYLD, HLA-DMB, MEF2C, PDE7A, RNASEH2B +4 more | |
| Innate lymphoid cells | NK JAK3 Signaling activation | APLP2, ATP8B4, CALCOCO2, ERLEC1, FLOT1, FUT8, FYCO1, HADHB +10 more | View in SCUBA |
| Macrophages | MITF Lysosomal Program Lysosomal & pahgocytosis | ABHD3, ARSB, C2CD5, CERS6, CHST11, CNST, DCTN4, FBXL20 +25 more | View in SCUBA |
| Mucosal-associated invariant T cell | Calcium Signal Integration TCR Signaling | ARB2A, CAMK2D, DOCK10, ELMO1, EXOC4, FCHSD2, FNDC3A, FOXN3 +20 more | |
| Neutrophils | Stress Kinase Signaling Stress | APBB1IP, HIPK3, IGF1R, MAP3K5, MEF2A, NEK7, PARP8, RAP1GAP2 +2 more |
About the gene
| Synonyms | PP6-ARS-B |
|---|---|
| Chromosome | 2: 196967017-197311173 |
| Predicted location | Intracellular |
| Essential gene | No |
| Protein class | Predicted intracellular proteins |
Function
Putative regulatory subunit of protein phosphatase 6 (PP6) that may be involved in the recognition of phosphoprotein substrates
Human Protein Atlas · Open Targets · UniProt
Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.