CNST — Consortin, connexin sorting protein
CNST belongs to a gene co-expression module in 4 of 28 SCUBA cell types. Each module groups genes that rise and fall together in that cell type; the genes it shares a module with are its closest co-expression partners there.
CNST's module in each cell type
| Cell type | Module | Shares the module with | |
|---|---|---|---|
| CD4⁺ T cells | TCR signaling activation TCR/AP1/NFKb pathway | CORO1B, DAPP1, ECI1, FAAH2, FCMR, GPCPD1, KLHL24, MLLT3 +8 more | View in SCUBA |
| Lymphatic endothelial | NF-κB Innate Signaling Inflammation | AKAP13, B4GALT5, BACH1, CHD2, DENND5A, HIVEP1, HIVEP2, IRAK2 +11 more | View in SCUBA |
| Macrophages | MITF Lysosomal Program Lysosomal & pahgocytosis | ABHD3, ANKRD44, ARSB, C2CD5, CERS6, CHST11, DCTN4, FBXL20 +25 more | View in SCUBA |
| Smooth muscle cells | Cytoskeletal Scaffolding Cytoskeletal | AKAP6, C3orf70, CTTNBP2, DACT3, IQGAP1, KIF13A, KLHL23, NTF3 +8 more | View in SCUBA |
About the gene
| Synonyms | C1orf71, FLJ32001, PPP1R64 |
|---|---|
| Chromosome | 1: 246566444-246668595 |
| Predicted location | Intracellular, Membrane |
| Essential gene | No |
| Protein class | Predicted intracellular proteins, Predicted membrane proteins |
Function
Required for targeting of connexins to the plasma membrane
Human Protein Atlas · Open Targets · UniProt
Gene annotation from the Human Protein Atlas and UniProt; see sources & licences.